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Payment
Can I pay by creditcard?
Yes, you can pay for you order by creditcard. We accept Mastercard, Visa and American Express.
Can I pay by Paypal?
Yes, you can pay for you order using Paypal. A Paypall transaction can be made during the checkout process. Orders placed directly in the webstore are free of additional costs.
Shipment
Which shipment carrier will be used to deliver my order?
We ship by UPS . Shipment on your organizations UPS or FedEx account is also possible, in this case an administrative surcharge of €20 will apply.
How long will shipment take?
Aim is to ship within a week, however some products are make to order. In most cases a few more days apply before the products to arrive at the country of destination.
In case of catalogue products which are made to order additional lead time might apply. This is indicated on the product page.
Discount
Do you offer an academic discount?
Micronit would like to offer everybody directly the best price without the need for asking, for that reason we don't offer academic discounts.
I'm purchasing on behalf of somebody else, can I get a distributor discount?
No, we do not offer discounts to distributors that are not appointed by Micronit.
Distributors
I'm located in the People's Republic of China. Do you have a distributor here?
Yes, we have a (non-exclusive) distributor in the PRC.
Contact details are:
Micro-Nano Cube Technology (Beijing) Co., LtdChaoyang DistrictBeijing Jiuxianqiao Electronic City, R&D Center Block A2 West sevenBeijing
Email: inquiry@microblox.cnPhone: 010-58237080
http://www.beijingec.com
I'm located in Japan. Do you have a distributor here?
Yes, we have a distributor in Japan.
Contact details are:
Kyodo International Inc.2-10-9, MiyazakiMiyamae-kuKawasaki-shi, Kanagawa-ken216-0033, Japan
phone: +81-44-853-2611 (main office)fax: +81-44-854-1979
e-mail: info@kyodo-inc.com
https://www.kyodo-inc.co.jp/
Should I order directly or does Micronit work with distributors?
In most cases it's possble to order directly at Micronit, only in Japan a distributor is required. For a more complete setup Darwin Microfluidics can support.
Product group: droplet generators
I need a pumping system for my setup. Which one do you recommend?
We recommend using a high precision pumping system. Regular syringe pumps often don't work very well for droplet generators. There are several high precision pumping systems on the market that work with different pumping principles.To name one, we'd like to mention that we have had positive experiences with the equipment Fluigent offers. https://www.fluigent.com/
Which flowrates should I use?
Advice on how to find the right flow rates and to to change the droplet size can be found under "Read More".
I only see streaks of fluids but no droplets. How do I get the droplets?
When you only see streaks of fluids its important to decrease your flowrate.
Instructions to find the right flow rate can be found under "Read More".
Which surfactants should I use?
Tween 20, Tween 80 and Emulseo FluoSurf™-O surfactant are used in combination with our chips.
See "Read More" for details.
How do I prevent clogging of my chips?
Clogging can only be avoided by working as cleanly as possible.
Typical sources of particles include:
- Dust from the air or open surfaces
- Larger particles or other contamination in the fluids
- Dried or solidified residues when re-using chips from previous runs
- Components within the fluidic setup (e.g., tubing, connectors, reservoirs)
- Residual particles remaining after cleaning
See “Read More” for detailed advice on minimizing these risks.
Should I use coated or uncoated droplet generators?
For water-in-oil droplets, use droplet generators with a hydrophobic coating.For oil-in-water droplets, no additional coating is needed.
Below more details on surface wetting properties are explained.Surface wetting propertiesThe contact angle between the fluid and the droplet generator surface is key for defining the stability of the wetting of the continuous phase. If the wetting is more preferential for the dispersed phase, pinning of the droplets to the channel can occur. The standard uncoated droplet generators of Micronit are glass based, thus hydrophilic and are suitable for making organic droplets in an aqueous phase (oil-in-water droplets). It is possible for Micronit to provide a coating which renders the surface of the droplet generators hydrophobic, thus suitable for making aqueous droplets in an organic phase (water-in-oil droplets). This coating is based on a fluorinated polymer and ensures the coated surface has a contact angle of more than 90° with water.
Product group: EOR
Which pressure and temperature can the EOR chip hold?
The EOR chip itself is manufactured from glass and can easily withstand up to 300⁰C. The chips are supplied in a black fluidic cartridge however, this cartridge can withstand up to 80⁰C.No sealant is used, the two layers of glass are fusion bonded together.The chip can withstand easily up to 100 bar. The external interfacing is more critical however. Our Fluidic Connect holder offers the largest pressure, up to 80 bars (maybe less at elevated temperatures). Please note that it might be helpful to practice a little with the Fluidic Connect holder first. You need to get the feeling to apply not too much force, which might break the chip, but enough to obtain sufficient sealing. It might be necessary to tighten a bit more when pressure and temperature are increased. Please remove the pressure before additional tightening.
I'm using the Fluidic Connect 4515 holder (part of high pressure bundle), what alignment and fluidic port should I use?
The fluidic ports are on positions 3,8Alignment can be done on positions 2,7 (or 4,9).
Product group: OOC
Is it possible to monitor oxygen levels?
It is possible to couple Micronit OOC devices to commercial optical readers for dissolved gases in the culture medium. This option allows for applications such as the monitoring of oxygen in the culture chamber.
Is my OOC system compatible with my imaging systems?
A document link can be found under "Read More".
The membrane is moving and flow is switching between top and bottom flow path. What is happening?
Always check that there’s no blockage in one of the flow paths, this can be verified by checking the amount of collected liquid in a specific time frame and compare it with the expected amount for the flow rate used.If this isn't the case, droplet formation on the end of the tubing is the problem. Each falling droplet affects the flow a bit, resulting in changes in flow rates. Resolve this by keeping the end of the tubing in the collection reservoir submerged in liquid.
How do I clean my resealable flow cell's / OOC top and bottom layers?
The glass layer without a gasket can be cleaned using the same methods commonly used for glass microscope slides. The gasket layer, however, requires more careful handling. For detailed instructions, see "Read More".
How do I sterilize my resealable flow cell's / OOC top and bottom layers?
Advice on sterilization of glass slides and glass slides without gasket can be found under "Read More".
What is the oxygen permeability data for the elastomer used?
More details on oxygen permeability can be found under "Read More".
Publication: Implementation of a dynamic intestinal gut-on-a-chip barrier model for transport studies of lipophilic dioxin congeners.
Implementation of a dynamic intestinal gut-on-a-chip barrier model for transport studies of lipophilic dioxin congeners.
Kulthong K, Duivenvoorde L, Mizera BZ, Rijkers D, Dam GT, Oegema G, Puzyn T, Bouwmeester H, Van Der Zande M.
RSC Advances. 2018; 8(57): 32440-32453
https://doi.org/10.1039/C8RA05430D
Publication: Microfluidic chip for culturing intestinal epithelial cell layers: Characterization and comparison of drug transport between dynamic and static models.
Microfluidic chip for culturing intestinal epithelial cell layers: Characterization and comparison of drug transport between dynamic and static models.
Kulthong K, Duivenvoorde L, Sun H, Confederat S, Wu J, Spenkelink B, de Haan L, Marin V, van der Zande M, Bouwmeester H.
Toxicol In Vitro. 2020 Jun;65:104815
https://doi.org/10.1016/j.tiv.2020.104815
Publication: Transcriptome comparisons of in vitro intestinal epithelia grown under static and microfluidic gut-on-chip conditions with in vivo human epithelia.
Transcriptome comparisons of in vitro intestinal epithelia grown under static and microfluidic gut-on-chip conditions with in vivo human epithelia.
Kulthong K, Hooiveld GJEJ, Duivenvoorde L, Miro Estruch I, Marin V, van der Zande M, Bouwmeester H.
Sci Rep. 2021 Feb 5;11(1):3234
https://doi: 10.1038/s41598-021-82853-6
Publication: Comparison of gene expression and biotransformation activity of HepaRG cells under static and dynamic culture conditions.
Comparison of gene expression and biotransformation activity of HepaRG cells under static and dynamic culture conditions
Duivenvoorde LPM, Louisse J, Pinckaers NET, Nguyen T, van der Zande M.
Sci Rep. 2021 May 14;11(1):10327.
https://www.nature.com/articles/s41598-021-89710-6
Product group: resealable
How do I clean my resealable flow cell's / OOC top and bottom layers?
The glass layer without a gasket can be cleaned using the same methods commonly used for glass microscope slides. The gasket layer, however, requires more careful handling. For detailed instructions, see "Read More".
How do I sterilize my resealable flow cell's / OOC top and bottom layers?
Advice on sterilization of glass slides and glass slides without gasket can be found under "Read More".
What is the oxygen permeability data for the elastomer used?
More details on oxygen permeability can be found under "Read More".
What are the dimension of the available view window using the resealable / OOC chip holder?
The available view window is 25x12mm, see "Read More" for details.
Tags
OOC (12) Publication (9) Droplet (8) Fluidic Connect Pro (7) Sheet nozzles (5) Resealable (5) Fluidic Connect 4515 (4) Prototyping and production (4) Distributor (3) Product development (3) Cleaning (2) Sideconnect (2) Pump (2) Flowrate (2) Payment (2) EOR (2) Shipment (2) Coating (2) Discount (2) Oxygen (1)